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KMID : 0360220110520030355
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Journal of the Korean Ophthalmological Society
2011 Volume.52 No. 3 p.355 ~ p.358
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A Case of Muir-Torre Syndrome
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Bae Kun-Ho
Kim Yoon-Duck
Woo Kyung-In
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Abstract
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Purpose: To present a rare case of Muir-Torre syndrome characterized by the association of sebaceous skin tumors and systemic malignancies.
Case Summary: A 65-year-old female visited our clinic with an irregular nodular mass of the right lower eyelid, which developed 1 year earlier. An excisional biopsy and lower lid reconstruction with Tenzel’s semicircular rotational flap was performed under local anesthesia. Histopathologic examination showed well-differentiated sebaceous cells, consistent with sebaceous adenoma. The patient had undergone total abdominal hysterectomy and lower anterior resection due to endometrial cancer and sigmoid colon cancer 5 years before, and nephroureterectomy due to papillary urothelial carcinoma 3 years before. Based on the history of systemic malignancy and sebaceous skin cancer, a diagnosis of Muir-Torre syndrome was made.
Conclusions: When a sebaceous gland tumor of the eyelids is detected, Muir-Torre syndrome should be included in the differential diagnosis, and systemic work-up for the internal malignancy must be performed.
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KEYWORD
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Eyelid tumor, Muir-Torre syndrome, Sebaceous, Systemic malignancy
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